Ha Pham

I am a R&D Group Leader at BellBrook Labs.

Previously, I was a postdoctoral researcher in Dr. Cho's group at the University of Illinois at Chicago.

I got my Ph.D in Chemistry at the University of Illinois at Chicago in May 2020 under the supervision of Dr. Lawrance Miller.

Here is my CV.

Here is my Google Scholar Profile.

Email: ha.phamthi91@gmail.com.

Research Interests

Cholesterol signaling, Time-gated luminescence microscopy, FRET-based biosensors, TR-FRET assay, gene manipulation.

Publications

1. Le A. T., Truong H. H., Nguyen P. T., Pham H. T., Kotsuba V. E., Soldatenkov A. T., Khrustalev V. N., Wodajo A. T., Synthesis and Molecular Structure of Dibenzo [4-(α-Thienyl-and α-Pyrrolyl)pyrido]aza-14-crown-4 Ethers, Macroheterocycles, 7(4), 386-390, 2014. (click here.)
2. Girdhar K., Benitez-Jones M., Pham H. T., Nelson M., Gruebele M., Chemla Y., The behavioral space of zebrafish locomotion and its neural network model, Bulletin of the American Physical Society, 2014 (clich here.)
3. Le A. T., Truong H. H., Nguyen P. T., Dao N. T., To T. H., Pham H. T., Soldatenkov A. T., Synthesis and biological activity of (γ-arylpyridino)-dibenzoaza-14-crown-4 ethers, Mendeleev Communications, 25(3), 224-225, 2015 (click here.)
4. Rosenhouse-Dantsker A., Pham H. T., Papadantonakis G. A. Chem 100 Laboratory Manual. Chicago: Hayden-McNeil, 2018. Print (click here.)
5. Ting Chen, Ha Pham, Ali Mohamadi, Lawrence W Miller, Single-chain lanthanide luminescence biosensors for cell-based imaging and screening of protein-protein interactions, iScience, Volume 23, Issue 9, 2020 (click here.)
6. Ha Pham, Lawrence W Miller, Lanthanide-based resonance energy transfer biosensors for live-cell applications, Methods in Enzymology; 2020 ( click here.)
7. Pawanthi Buwaneka, Arthur Ralko, Sukhamoy Gorai, Ha Pham, and Wonhwa Cho, Phosphoinositide binding activity of Smad2 is essential for its function in TGF-beta signaling, Journal of Biological Chemistry 297(5), 2021 ( click here.)
8. Ha Pham, Indira Singaram, Jiachen Sun, Arthur Ralko, Madalyn Puckett, Ashutosh Sharma, Alice Vrielink, and Wonhwa Cho, Development of a novel spatiotemporal depletion system for cellular cholesterol, Journal of Lipid Research, Volume 63, Issue 3, 100178, March 01, 2022. (click here.)
9. Ha Pham, Mona Hoseini Soaee, Andrei V Karginov, Lawrence W Miller FRET and LRET Biosensors for Cell-based Imaging and Screening of Rac1 Activation, Scientific Reports 12, no. 1 (2022): 5291. ( click here.)
10. Ha Pham, Meera Kumar, Anibal Ramos Martinez, Mahbbat Ali, and Robert G. Lowery, Development and validation of a generic methyltransferase enzymatic assay based on an SAH riboswitch, SLAS Discovery, Volume 29, Issue 4, 100161, 2024. ( click here.)

Patents

1. Le A., Soldatenkov T., Nguyen P., To T., Truong H., Pham H., 2013. Synthesis of (γ-arylpyridino)-dibenzoaza-14-crown-4 ether derivatives and their cytotoxicity on four cancer cell lines. Patent No. VN 19514.

Selected presentations

• Mahbbat Ali, Ha Pham, Anibal Ramos-Martinez, Robert Lowery, BellBrook Labs, Madison WI; Abstract 4184: Development of a homogenous poly(ADP-ribose) assay for screening and profiling PARP inhibitors. Cancer Res 15 April 2025; 85 (8_Supplement_1): 4184. Click here.
• Ha Pham, Mahbbat Ali, Anibal Ramos-Martinez, Robert Lowery, BellBrook Labs, Madison WI; Abstract 4237: Homogenous detection of O-Acetyl-ADP-ribose as a generic HTS assay method for SIRTs. Cancer Res 15 April 2025; 85 (8_Supplement_1): 4237. Click here.
• Ha Pham, Mahbbat Ali, Anibal Ramos Martinez, Robert Lowery, BellBrook Labs, Madison WI; Abstract 3113: Development of HTS enzymatic assays for WRN helicase and exonuclease functions. Cancer Res 15 March 2024; 84 (6_Supplement): 3113. Click here.
• Mahbbat Ali, Ha Pham, Anibal Ramos Martinez, Robert Lowery, BellBrook Labs, Madison WI; Abstract 3114: Development of HTS enzymatic assays for RNA helicases: DDX3, DDX5, DDX17, RIG-1 and MDA5. Cancer Res 15 March 2024; 84 (6_Supplement): 3114. Click here.
• High Dynamic-range LRET Biosensors for Live Cell Imaging and HTS, UIC Research Symposium 2019
• Biophysical Neuron Model of Free Swimming Zebrafish: “The Neurosim Fish” , Poster Session, Summer Undergraduate Research, UIUC, Il, August 2013.
• Synthesis of Aza-crown Ethers and Their Bioactivity, Student Research Workshop, VNU, March 2013.

Honors and Awards

• Postdoctoral Small Scholarship Award, UIC, 2020.
• Teaching Assistant of the year, Department of Chemistry, UIC, 2016.
• POSCO scholarship, Posco T.J.Park Fund Foundation, 2011-2013. Click here for an essay that I wrote for their newsletter.
• The prominent young students of VNU University of Science, 2013.

Other Services

Volunteer for Boys and Girls club of Chicago (2016-2017)

• Every week, we helped young students do hands-on scientific experiments and activities. The main goal of this program is to motivate them to study science. Click here to learn more about this wonderful program. Click here for a picture of myself with other mentors and students.

Laboratory Coordinator for CHEM 100 at UIC

• Coordinated activities in the chemistry lab; procured materials, services and facilities necessary for science instruction.

Trees

Click here for a wonderful passage by Hermann Hesse about trees.